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Three cases of translocation (8;16)(p11;p13) observed in acute myelomonocytic leukemia: A new specific subgroup?

✍ Scribed by J.L. Laï; M. Zandecki; J.P. Jouet; J.B. Savary; A. Lambiliotte; F. Bauters; A. Cosson; M. Deminatti

Book ID: 119103631
Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 483 KB
Volume: 27
Category: Article
ISSN: 0165-4608
DOI: 10.1016/0165-4608(87)90265-2

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The inv(16)(p13q22) masked by different translocations was detected by fluorescence in situ hybridization (FISH) and confirmed by molecular analysis in three adult patients presenting with acute myeloid leukemia (AML)-M2 (cases 1 and 3) and M4Eo (case 2). Cytogenetic analysis revealed 47,XX,t(9;16)(