Thoracic neural crest tumors in Beckwith-Wiedemann syndrome

✍ Scribed by Thornburg, Courtney D. ;Shulkin, Barry L. ;Castle, Valerie P. ;McAllister-Lucas, Linda M.

• Book ID: 102521269
• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 73 KB
• Volume: 41
• Category: Article
• ISSN: 0098-1532
• DOI: 10.1002/mpo.10404

✦ Synopsis

differentiation and histologic type of the ependymoma, age at diagnosis, degree of surgical resection or prior treatment and subsequent development of extraneural metastases was found [4]. The exact route of extraneural metastases is not known, but in the vast majority metastases occurred in the wake of craniotomy, suggesting iatrogenic vascular seeding [3]. Typically, extraneural metastases of ependymoma occur in the lungs, pleura, and lymph nodes while metastases to the mediastinum, liver, bone, and diaphragmatic muscle are even less common [4]. In most cases, the existence of pleuropulmonary metastases was disclosed only at autopsy usually coexisting with CNS recurrence and systemic metastases [5]. Extraneural metastases or relapses of ependymoma are extremely rare but physicians caring for ependymoma patients must remain aware of this possible complication.