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THK523 selectively binds to neurofibrillary tangles and neuropils in people with Alzheimer's disease

✍ Scribed by Fodero-Tavoletti, Michelle; Okamura, Nobuyuki; Taylor, Leanne; Furumoto, Shozo; McLean, Catriona; Mulligan, Rachel S.; Birchall, Ian; Harada, Ryuichi; Masters, Colin; Yanai, Kazuhiko; Rowe, Christopher; Kudo, Yukitsuka; Villemagne, Victor

Book ID
122486848
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
519 KB
Volume
9
Category
Article
ISSN
1552-5260

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## Abstract To assess the relationship between dementia, neuronal loss, and neuropathological findings in Alzheimer's disease (AD), we counted the number of neurons, senile plaques, and neurofibrillary tangles in a high‐order association cortex. We studied the superior temporal sulcus of 34 individ