๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Thiyl- and thiyl-peroxyl radicals produced from the irradiation of antioxidant thiol compounds

โœ Scribed by M. Tamba; A. Torreggiani; O. Tubertini

Book ID
103990912
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
359 KB
Volume
46
Category
Article
ISSN
0969-806X

No coin nor oath required. For personal study only.

โœฆ Synopsis

The transients involved in the mechanism of protection by thiol compounds against oxidative damage have been characterized by pulse radiolysis technique. The oxidizing properties of both thiyl (RS.) and thiyl-peroxyl radical (RSOO.), with E lying in the range +0.9 to +1.0 V, are well emphasized from the rates for their interactions with nucleophilio agents, including naturally occurring antioxiclants. By applying a plausible kinetic treatment to the decay pattern of RSOO., the rates for both the interaction of the radical with the parent thiol and the structural rearrangement to sulphonyl radical (RSO2") were measured to be 1.4 x 106 mol'ldm3s "1 and 1.4 x 103s "1, respectively. The roles of thiol-derived radicals in oxidative damage in biological systems are discussed.

๐Ÿ“œ SIMILAR VOLUMES

[Methods in Enzymology] Biothiols Part A
[Methods in Enzymology] Biothiols Part A Monothiols and Dithiols, Protein Thiols, and Thiyl Radicals Volume 251 || [3] Kinetic factors that control the fate of thiyl radicals in cells
โœ Wardman, Peter ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier ๐ŸŒ English โš– 820 KB

Pt. A. Monothiols And Dithiols, Protein Thiols, And Thiyl Radicals -- Pt. B. Glutathione And Thioredoxin: Thiols In Signal Transduction And Gene Regulation. Edited By Lester Packer. Includes Bibliographical References And Index.