Thiostrepton, proteasome inhibitors and FOXM1
β Scribed by Gartel, Andrei L.
- Book ID
- 118131907
- Publisher
- Landes Bioscience
- Year
- 2011
- Tongue
- English
- Weight
- 174 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1538-4101
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## Abstract The ubiquitinβproteasome pathway has emerged as a central player in the regulation of several diverse cellular processes. Here, we describe the important components of this complex biochemical machinery as well as several important cellular substrates targeted by this pathway and exampl
Protein degradation plays an important role in the control and regulation of many crucial biological functions, ranging from cell cycle progression to presentation of viral antigens for scrutiny by cells of the immune system. At the heart of many of these catabolic events is the multicatalytic prote