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Thioredoxin 1 Down-regulates but Thioredoxin Reductase Up-regulates ROS Generation and Secretion/expression of MCP-1 in Endothelial-like cells

โœ Scribed by Xun Shen; Beidong Chen; Zhen-Bo Liu; Dandan Guan; Dandan Guan


Book ID
113631577
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
406 KB
Volume
49
Category
Article
ISSN
0891-5849

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Transcriptional regulation of thioredoxi
โœ Atsuko Sakurai; Michie Nishimoto; Seiichiro Himeno; Nobumasa Imura; Masafumi Tsu ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 358 KB

## Abstract Thioredoxin reductase (TrxR) is a selenoprotein that catalyzes the reduction of the active site disulfide of thioredoxin (Trx), which regulates the redox status of the cells. In the present study, we found that TrxR1, one of the three TrxR isozymes, was induced by cadmium as well as tum