Thiophene-2,5-dicarboxylic acid bis-aryl(alkyl) amides

✍ Scribed by Metin Koparır; Ahmet Cansız; Ahmet Çetin

• Book ID: 102229956
• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 61 KB
• Volume: 16
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20153

✦ Synopsis

A base-catalyzed condensation of diacetamido sulfides [(RNHCOCH 2 ) 2 S)] with glyoxal affording thiophene-2,5-dicarboxylic acid bis-aryl-(alkyl)amides has been accomplished under mild conditions. Excellent results were readily obtained when R was a substituted 3-nitrophenyl, 4-nitrophenyl, 4chlorophenyl group, but the yield was poor when R was cyclohexyl. Unknown compounds were characterized by elemental analyses,