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Thiopental inhibits NF-κB activation in human glioma cells and experimental brain inflammation

✍ Scribed by Takashi Ichiyama; Miki Nishikawa; James M Lipton; Tomoyo Matsubara; Hayashi Takashi; Susumu Furukawa


Book ID
113997319
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
381 KB
Volume
911
Category
Article
ISSN
0006-8993

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The neuropeptide ␣-melanocyte-stimulating hormone (␣-MSH) modulates inflammation by inhibiting production of proinflammatory cytokines. Using a plasmid vector encoding ␣-MSH, we examined whether autocrine ␣-MSH inhibits activation of the nuclear transcription factor NF-B, a factor that is essential