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Thioglycoligases: Mutant Glycosidases for Thioglycoside Synthesis

✍ Scribed by Michael Jahn; Jennifer Marles; R. Antony J. Warren; Stephen G. Withers

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 93 KB
Volume: 42
Category: Article
ISSN: 0044-8249
DOI: 10.1002/anie.200390114

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✦ Synopsis

Scheme 1. Mechanism of a retaining glycosidase: Glycosylation and deglycosylation with wild-type (a) and acid/base mutant (b). DNP ¼ dinitrophenyl, Nu ¼ nucleophile.

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