Thio analogs of pyrimidine bases: Syntheses and EIMS study of new ortho-(meta- and para-)bromobenzyl s-mono and S-N-1-disubstituted 5-morpholinomethyl(5-piperidinomethyl)-2-thiouracils

✍ Scribed by Elżbieta Wyrzykiewicz; Tomasz Pospieszny

• Book ID: 102338252
• Publisher: Journal of Heterocyclic Chemistry
• Year: 2007
• Tongue: English
• Weight: 402 KB
• Volume: 44
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570440109

✦ Synopsis

Eleven new ortho-(meta-and para-)bromobenzyl S-mono and S-N-1-disubstituted derivatives of 5morpholinomethyl-2-thiouracil (MMTU) and 5-piperidinomethyl-2-thiouracil (PMTU) have been prepared and their EI induced mass spectral fragmentation has been investigated. It has been shown that the data derived from EIMS spectra can be used to differentiate the isomers.