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Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARγ-independent mechanism

✍ Scribed by M. Artwohl; C. Fürnsinn; W. Waldhäusl; T. Hölzenbein; G. Rainer; A. Freudenthaler; M. Roden; S. M. Baumgartner-Parzer

Book ID: 105817964
Publisher: Springer
Year: 2005
Tongue: English
Weight: 215 KB
Volume: 48
Category: Article
ISSN: 0012-186X
DOI: 10.1007/s00125-005-1672-z

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## Abstract The nuclear transcription factor peroxisome proliferator‐activated receptor‐gamma (PPARγ) has been identified as an important therapeutic target in murine models of colorectal cancer (CRC). To examine whether PPARγ inhibition has therapeutic effects in late‐stage CRC, the effects of PPA