๐”– Bobbio Scriptorium
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Thiazoles and Thiopyridines: Novel Series of High Affinity h5HT7 Ligands.

โœ Scribed by Christopher G. Thomson; Margaret S. Beer; Neil R. Curtis; Helen J. Diggle; Emma Handford; Janusz J. Kulagowski


Publisher
John Wiley and Sons
Year
2004
Weight
93 KB
Volume
35
Category
Article
ISSN
0931-7597

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A novel series of arylpiperazines with h
โœ P. John Murray; Lee A. Harrison; Martin R. Johnson; Graeme M. Robertson; David I ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 210 KB

A novel series of arylpiperazines has been synthesised which show high affinity for dopamine D 3 receptors. Several of these compounds exhibit ca. 100 fold selectivity for the dopamine D 3 receptor over D 1 , D 2 and D 4 receptors. In vivo studies suggest that 4 (GR103691) may have an atypical antip