Theα1 andα2 domains of H-2 class I molecules interact to form unique epitopes
✍ Scribed by Tsugiyasu Kanda; Katherine LaPan; Hiroaki Takahashi; Ettore Appella; Jeffrey A. Frelinger
- Publisher
- Springer-Verlag
- Year
- 1987
- Tongue
- English
- Weight
- 598 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0093-7711
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Adhesion to collagens by most cell types is mediated by the integrins a1b1 and a2b1. Both integrin a subunits belong to a group which is characterized by the presence of an I domain in the N-terminal half of the molecule, and this domain has been implicated in the ligand recognition. Since purified
The rat major histocompatibility complex (RT1-B region) codes for two sets of class II molecules (Ia antigens) referred to as A and E. Each class II molecule is composed of two glycoprotein chains called the A~ and Aa or E~ and E~. Two cDNA clones encoding rat A, chains were identified from cDNA der