𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Thevγ chain of fetal hemoglobin of the orangutan

✍ Scribed by W. A. Schroeder; J. Roger Shelton; Joan B. Shelton; T. H. J. Huisman

Book ID
104784052
Publisher
Springer
Year
1978
Tongue
English
Weight
153 KB
Volume
16
Category
Article
ISSN
0006-2928

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✦ Synopsis

Previous studies suggested that orangutans have nonallelic structural genes for their 7 chains, because either a threonyl or an alanyl residue may occupy position 135. Further investigation has now detected that position 75 may have either an isoleucyl or a valyl residue. From available evidence, the isoleucyl and threonyl residues are in one chain and the valyl and alanyl in the other. Orangutans appear to be homozygous for the two types of nonallelic genes.

📜 SIMILAR VOLUMES

Homozygotes for the hereditary persisten
Homozygotes for the hereditary persistence of fetal hemoglobin: The ratio ofGγ toAγ chains and biosynthetic studies
✍ B. Ringelhann; C. T. A. Acquaye; J. H. Oldham; F. I. D. Konotey-Ahulu; G. Yawson 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 594 KB

Two sons of a previously reported Ghanaian homozygote for the hereditary persistence of fetal hemoglobin (HPFH) (Ringelhann et al., 1970) also are HPFH homozygotes. In addition, another unrelated adult Ghanaian homozygote has been detected. All of these Ghanaian homozygotes as well as three American