✦ LIBER ✦

Theta Oscillations in the Hippocampus

✍ Scribed by György Buzsáki

Book ID: 117608089
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 542 KB
Volume: 33
Category: Article
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(02)00586-x

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✦ Synopsis

Theta oscillations represent the “on-line” state of the hippocampus. The extracellular currents underlying theta waves are generated mainly by the entorhinal input, CA3 (Schaffer) collaterals, and voltage-dependent Ca2+ currents in pyramidal cell dendrites. The rhythm is believed to be critical for temporal coding/decoding of active neuronal ensembles and the modification of synaptic weights. Nevertheless, numerous critical issues regarding both the generation of theta oscillations and their functional significance remain challenges for future research.

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