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Thermolabile and thermostable human platelet phenol sulfotransferase

โœ Scribed by Christoph Reiter; Gabriel Mwaluko; Joel Dunnette; Jon Loon; Richard Weinshilboum


Book ID
112340978
Publisher
Springer-Verlag
Year
1983
Tongue
English
Weight
945 KB
Volume
324
Category
Article
ISSN
0028-1298

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โœ R. Arlen Price; Nancy J. Cox; Richard S. Spielman; Jon A. Van Loon; Bonnie L. Ma ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 809 KB

Sulfate conjugation is an important pathway in the biotransformation of drugs and neurotransmitters. The thermolabile (TL) form of the enyzme phenol sulfotransferase (PST) catalyzes the sulfation of catecholamine neurotransmitters and drugs such as methyldopa and acetaminophen. Platelet TL PST activ