## Abstract The thermodynamics of barnase denaturation has been studied calorimetrically over a broad range of temperature and pH. It is shown that in acidic solutions the heat denaturation of barnase is well approximated by a 2โstate transition. The heat denaturation of barnase proceeds with a sig
Thermodynamics of unfolding
โ Scribed by Kauzmann, Walter
- Book ID
- 109748507
- Publisher
- Nature Publishing Group
- Year
- 1987
- Tongue
- English
- Weight
- 338 KB
- Volume
- 325
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/325763a0
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## Abstract The heat capacity, enthalpy, entropy, and Gibbs energy changes for the temperatureโinduced unfolding of 11 globular proteins of known threeโdimensional structure have been obtained by microcalorimetric measurements. Their experimental values are compared to those we calculate from the c