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Thermodynamics of HMGB1 Interaction with Duplex DNA†

✍ Scribed by Müller, Susanne; Bianchi, Marco E.; Knapp, Stefan

Book ID
115499738
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
107 KB
Volume
40
Category
Article
ISSN
0006-2960

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HIV-1 reverse transcriptase (HIV-1 RT) is a multifunctional enzyme responsible for converting viral RNA into preintegrative DNA during the early stages of viral infection. DNA polymerase and RNase H activities are required, and several conformationally distinct primer-templates must be accommodated