✦ LIBER ✦

Thermodynamic treatment of ligand-receptor interactions

✍ Scribed by Vito Di Noto; Lisa Dalla Via; Antonio Toninello; Maurizio Vidali

Book ID: 102945581
Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 800 KB
Volume: 5
Category: Article
ISSN: 1022-1344
DOI: 10.1002/mats.1996.040050201

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

This work reports the development of a physico‐chemical model for ligand‐receptor interactions. It considers receptors having groups of different binding sites in equilibrium and far from equilibrium where each of these may have multiple occupancies. The obtained results under appropriate simplifications give the well known Scatchard, Hill and Adair relations and provide a very interesting tool for studying receptor‐ligand phenomena and for determining the related parameters and interaction energies.

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