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Thermodynamic Study of Enantioseparation of Mitotane by Supercritical Fluid Chromatography

✍ Scribed by Antelo, Francine; Santana, Cesar Costapinto; Moitinho Alves, Tito Lívio; Barreto, Amaro Gomes

Book ID
115479663
Publisher
Taylor and Francis Group
Year
2012
Tongue
English
Weight
263 KB
Volume
47
Category
Article
ISSN
0149-6395

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## Abstract The separation of racemic paroxol, a key precursor of __trans__‐(−)‐paroxetine, on Chiralpak AD‐H, an amylose‐based chiral stationary phase, by supercritical fluid chromatography was studied. Pulse experiments were investigated using supercritical carbon dioxide modified with methanol (