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Thermodynamic studies on the interaction between nucleic acid and drug by calorimetry

✍ Scribed by K. Kano; Y. Baba; A. Kagemoto

Book ID
107859055
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
347 KB
Volume
88
Category
Article
ISSN
0040-6031

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## Abstract We have shown previously that the N‐methylpridyl group vibrations of water‐soluble porphyrins, M(TMpy‐P4), are shifted to lower frequencies (0.5–2.6 cm^βˆ’1^) as a result of coulombic interaction between the N^+^‐CH~3~ group of M(TMpy‐P4) and the PO~2~ group of a nucleic acid. We have now