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Thermodynamic parameters of the α-methyl aspartate-aspartate aminotransferase interaction

✍ Scribed by Gordon G. Hammes; John F. Tancredi


Book ID
115731402
Publisher
Elsevier Science
Year
1967
Weight
119 KB
Volume
146
Category
Article
ISSN
0005-2744

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The effect of potassium depolarization and N-methyl-D-aspartate (NMDA) on the activity of aspartate aminotransferase (AAT; EC 2.6.1.1), an enzyme suggested to be involved in neurotransmitter glutamate synthesis, was studied in cultured cerebellar granule neurons. Both KCI and NMDA increased AAT acti