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Thermodynamic parameters of ionization of 5-(2-substituted phenylazo) barbituric acids

✍ Scribed by Mamdouh S. Masoud; S.A.Abou Ali; G.Y. Ali; I.M. Abed


Book ID
103412153
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
708 KB
Volume
122
Category
Article
ISSN
0040-6031

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## Abstract A sodium derivative of 1,3‐dimefhylbarbituric acid or 1,3‐diethyl‐2‐thiobarbituric acid undergoes an efficient monoacylation at C5 by the reaction with ω‐chloroalkanoyl chloride or diacid dichloride in the presence of pyridine in tetrahydrofuran. A nucleophilic displacement of the chlor