Thermochemistry of 6-propyl-2-thiouracil: An experimental and computational study
✍ Scribed by Szterner, Piotr; Galvão, Tiago L.P.; Amaral, Luísa M.P.F.; Ribeiro da Silva, Maria D.M.C.; Ribeiro da Silva, Manuel A.V.
- Book ID
- 122206397
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 851 KB
- Volume
- 588
- Category
- Article
- ISSN
- 0040-6031
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## Abstract 6‐n‐Propyl‐2‐thiouracil‐6−^14^C was prepared from sodium butyrate‐1−^14^C, with a radiochemical yield of 34%. Butyryl chloride‐1−^14^C was prepared from butyric acid‐1−^14^C and condensed with sodio ethylacetoacetate to yield ethyl β‐oxohexanoate‐β−^14^C. The β‐keto ester was condensed
Two o f t h e m i n o r m e t a b o l i t e s o f t h e a n t i t h y r o i d d r u g 6 -p r o p y l -2t h i o u r a c i l ( I ) have been i s o l a t e d f r o m r a t u r i n e i d e n t i f i e d as S-methyl-6 -p r o p y l -2 -t h i o u r a c i l