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Thermocatalytic and thermal isomerization of 3-phenyl-5-methoxyisoxazole

โœ Scribed by M. I. Komendantov; R. R. Bekmukhametov


Book ID
112326131
Publisher
Springer US
Year
1975
Tongue
English
Weight
73 KB
Volume
11
Category
Article
ISSN
0009-3122

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Synthesis of 3-phenyl-5-(trifluoromethyl
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Reaction of 4,4,4-trifluoro-1-phenyl-1,3-butanedione with hydroxylamine led to the formation of 5hydroxy-3-phenyl-5-(trifluoromethyl)-4,5-dihydroisoxazole which was dehydrated to 3-phenyl-5-(trifluoromethyl)isoxazole. This isomer can also be synthesized by reaction of 4-chloro-4-phenyl-1,1,1-trifluo