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Thermo-Responsive Polymer Brushes as Intelligent Biointerfaces: Preparation via ATRP and Characterization

✍ Scribed by Kenichi Nagase; Minami Watanabe; Akihiko Kikuchi; Masayuki Yamato; Teruo Okano


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
634 KB
Volume
11
Category
Article
ISSN
1616-5187

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✦ Synopsis


Abstract

PIPAAm‐brush grafted glass substrates with various graft densities and chain lengths were prepared via surface‐initiated ATRP. Temperature‐dependent physicochemical properties of the surfaces were characterized by means of ATR/FT‐IR spectroscopy, XPS, AFM, and contact angle measurements. ATRP conditions influence the amount of grafted PIPAAm and the surface wettability and roughness of the substrate. Fibronectin adsorption and EC adhesion increased with decreasing density of PIPAAm brushes. EC adhesion was diminished with increasing PIPAAm graft length. Thus, the preparation of PIPAAm brush surface with various graft densities and chain lengths using the surface‐initiated ATRP is an effective method for modulating thermo‐responsive properties of surfaces.
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