Thermo-resistance based micro-calorimeter for continuous chemical enthalpy measurements
✍ Scribed by G. Velve Casquillas; F. Bertholle; M. Le Berre; S. Meance; L. Malaquin; J.J. Greffet; Y. Chen
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 346 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0167-9317
No coin nor oath required. For personal study only.
✦ Synopsis
We present a thermo-resistance based micro-calorimeter using a glass/platinum/PDMS prototyping technology which is more flexible than the existing silicon based technology for lab on a chip device integration. Resistance monitoring and fluid injection techniques are optimized in order to reduce thermal noises and improve the detection sensibility. We used neutralization acid-base reaction to evaluate the device capability in determination of both reagent concentration and reaction enthalpy. We also performed a glucose/glucose oxydase enzymatic reaction to illustrate the advantage of using PDMS device for the studies of aerobic reaction.