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Thermal valence rearrangements of heterocycles, 3. A key aziridine intermediate of the Δ4-isoxazoline-pyrrole rearrangement

✍ Scribed by Mullen, George B. ;Bennett, Grace A. ;Georgiev, Vassil St.


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
158 KB
Volume
1990
Category
Article
ISSN
0947-3440

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✦ Synopsis


Abstract

Utilizing the spiro[adamantane‐Δ^4^‐isoxazoline] precursor 10, a key 2‐acylaziridine intermediate (11) has been isolated, thus providing conclusive evidence that an initial ring contraction may be considered to be the first step of the Δ^4^‐isoxazoline‐pyrrole rearrangement.