Inclusion compounds containing a drug: s
✍
Petra Bombicz*; Edit Forizs*; János Madarász; Andrea Deák; Alajos Kálmán
📂
Article
📅
2001
🏛
Elsevier Science
🌐
English
⚖ 151 KB
Syntheses, crystal structures and comparative analytical investigations on the first two inclusion compounds of an antiepileptic drug, nitrazepam (1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one) are reported. The biologically active molecule forms isostructural clathrates with diaquadiethan