Thermal promotion of the cobalt catalyzed intramolecular Pauson-Khand reaction — An alternative experimental protocol for cyclopentenone synthesis

✍ Scribed by David B. Belanger; Donogh J.R. O'Mahony; Tom Livinghouse

• Book ID: 104259981
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 195 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)01693-1

✦ Synopsis

Heat alone has been found sufficient to promote intramolecular Pauson-Khand cyclizations catalyzed by high purity Co2(CO)s. The existence of a very narrow thermal window (e.g., 60 °C -70 °C) for the attainment of efficient catalysis is a noteworthy characteristic of this process.