Thermal Production and Reactions of Organic Ions at Atmospheric Pressure

✍ Scribed by Hao Chen; Zheng Ouyang; R. Graham Cooks

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 165 KB
• Volume: 118
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/ange.200600660

✦ Synopsis

Ionization of nonvolatile compounds has been accomplished by a wide selection of desorption ionization (DI) methods in which the sample is converted from the condensed phase into vapor-phase ions by high-energy particles (neutral species or ions with energies of 5 keV-100 MeV), photon beams (UV or IR energy range), or high electric fields (ca. 10 10 V m À1 ). Particular examples include secondary-ion mass spectrometry (SIMS), [1] fast atom bombardment (FAB), [2,3] plasma desorption (PD), [4] laser desorption (LD), [5,6] and field desorption (FD). [7] We now report a simple desorption method in which organic ions are generated efficiently by heating organic salts at atmospheric pressure; we also report reactions of these ions under ambient conditions. Although thermal ionization of low ionization energy elements is well-known, [8,9] atmospheric-pressure thermal desorption ionization (APTDI) of organic ions, as reported here, is unprecedented. Appropriate choices of the matrix and solvent strongly increase ion