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Thermal Denaturation of Collagen Analyzed by Isoconversional Method

✍ Scribed by Sergey Vyazovkin; Luc Vincent; Nicolas Sbirrazzuoli

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
138 KB
Volume
7
Category
Article
ISSN
1616-5187

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✦ Synopsis

Abstract

An isoconversional method is proposed to be used for evaluating activation energy of protein denaturation. Applied to DSC data on collagen denaturation, the method yields an activation energy that decreases throughout the process. The Lumry‐Eyring model gives an explanation for this decrease and affords estimates for the enthalpy of the reversible step and the activation energy of the irreversible step of denaturation. The reversible unfolding is detectable by multi‐frequency temperature‐modulated DSC.

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πŸ“œ SIMILAR VOLUMES

Study of collagen denaturation kinetics
Study of collagen denaturation kinetics by dynamic mechanical methods
✍ S. Reich; J. Yonath πŸ“‚ Article πŸ“… 1968 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 172 KB

## Study of Collagen Denaturation Kinetics by Dynamic Mechanical Met hods Denaturation or melting of collagen fibers is accompanied by an appreciable contraction. It may occur as a fairly sharp transition upon heating the fiber or increasing the concentration of a contractile salt solution in whic