Thermal cataract formation in rabbits

✍ Scribed by Piró Kramár; Carrol Harris; Arthur W. Guy

• Book ID: 102759943
• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 648 KB
• Volume: 8
• Category: Article
• ISSN: 0197-8462
• DOI: 10.1002/bem.2250080408

✦ Synopsis

Intraocularly circulating hot water was used to produce cataracts in nine eyes of seven rabbits by maintaining their retrolental temperatures between 43 degrees C and 45 degrees C. A rapid rate of heating (1.3 degrees C/min) plus a sharp temperature gradient across the eye may have been contributing factors in the consistent production of cataracts at these temperatures. Biomicroscopy and light microscopy showed lens changes similar to those associated with acute exposure to microwave radiation. These findings support the assumption that microwave cataractogenesis is due to the local production of elevated temperatures.