Dissolution behavior of crystalline solv
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Eli Shefter; Takeru Higuchi
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Article
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1963
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John Wiley and Sons
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English
β 976 KB
Relative rates of dissolution of several crystalline steroids, xanthines, and other solid drugs have been measured to determine the effect of solvate formation on this property. Equations have been derived relating the solubility products and diffusional constants to rates of solution of or anic sol