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Thermal and pH-Induced Conformational Changes of a β-Sheet Protein Monitored by Infrared Spectroscopy †

✍ Scribed by Chehín, Rosana; Iloro, Ibón; Marcos, María José; Villar, Enrique; Shnyrov, Valery L.; Arrondo, José Luis R.


Book ID
118143090
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
121 KB
Volume
38
Category
Article
ISSN
0006-2960

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## Abstract Acutolysin A isolated from the venom of __Agkistrodon acutus__ is a protein of 22 kDa with marked haemorrhagic and proteolytic activities. The metal ions‐ and pH‐induced conformational changes of acutolysin A have been studied by following fluorescence and activity measurements. Here, w