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Thermal activation of hexosaminidase A in a genetic compound with Tay-Sachs disease

✍ Scribed by Y. Ben-Yoseph; M. S. Baylerian; T. Momoi; H. L. Nadler

Publisher
Springer
Year
1983
Tongue
English
Weight
743 KB
Volume
6
Category
Article
ISSN
0141-8955

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Long-term intracellular retention of hexosaminidase A by Tay-Sachs disease brain and lung cells in vitro
✍ Steven E. Brooks; Linda M. Hoffman; Daniel Amsterdam; Masazumi Adachi; Larry Sch πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 493 KB πŸ‘ 1 views

## Abstract Enzyme‐replacement treatment for metabolic storage disorders has been widely studied using model cell culture systems. This study determines the long‐term fate of human hexosaminidase A supplied to Tay‐Sachs disease brain and lung cells. Hex A retention studies showed that the incorpora