Therapy-related malignancies following treatment of germ cell cancer
✍ Scribed by Christian Kollmannsberger; Jörg T. Hartmann; Lothar Kanz; Carsten Bokemeyer
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- French
- Weight
- 98 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0020-7136
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With the use of cisplatin-based combination chemotherapy, metastatic testicular germ-cell tumors can be cured in 70% to 80% of patients. The combination of cisplatin, etoposide and bleomycine (PEB) is considered standard therapy.
## Abstract We investigated the risk of second malignancies among 29,511 survivors of germ‐cell testicular cancer recorded in 13 cancer registries. Standardized incidence ratios (SIRs) were estimated comparing the observed numbers of second malignancies with the expected numbers obtained from sex‐,