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Therapy-related chronic myelomonocytic leukemia with unique chromosomal abnormalities: Monosomy 7 and t(12;17)(p13;q11.2)

โœ Scribed by Thein Hlaing Oo; Lawrence Kenney


Book ID
101439316
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
237 KB
Volume
82
Category
Article
ISSN
0361-8609

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CBP, which is located on 16p13 and encodes a transcriptional adaptor/coactivator protein, has been shown to fuse by the t(8;16)(p11;p13) translocation to MOZ on 8p11 in acute myeloid leukemia. We found a t(11;16)(q23;p13) in a child with therapy-related chronic myelomonocytic leukemia. Subsequent re