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Therapy-related acute myeloid leukemia with minimal myeloid differentiation (AML-MO) associated with a t(11;19)(q23;p13.3) translocation

โœ Scribed by Suehiro, Youko; Uike, Naokuni; Kumagawa, Midori; Goto, Tatsuro; Muta, Koichiro; Kozuru, Mitsuo

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
102 KB
Volume
55
Category
Article
ISSN
0361-8609

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CBP, which is located on 16p13 and encodes a transcriptional adaptor/coactivator protein, has been shown to fuse by the t(8;16)(p11;p13) translocation to MOZ on 8p11 in acute myeloid leukemia. We found a t(11;16)(q23;p13) in a child with therapy-related chronic myelomonocytic leukemia. Subsequent re