The novel anti-estrogen EM-800 and medroxyprogesterone acetate (MPA) inhibit estrone (E 1 )-stimulated growth of dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in a rat model. After 65 days, ovariectomy (OVX) decreased total tumor area to 9.6 ؎ 3.9% of initial size, while E 1 (1.0 µg, s.c.,
Therapy of dimethylbenzanthracene-induced mammary carcinomas in the rat by selective inhibition of steroidogenesis
✍ Scribed by John M. Levin; Allen S. Goldman; Francis E. Rosato; Ernest E. Rosato
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 424 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0008-543X
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