Six patients with chronic type B hepatitis were treated with adenine arabinoside 5'-monophosphate at a dosage of 10 to 15 mg per kg per day for 10 days. All demonstrated an immediate and marked decrease in serum hepatitis B virus DNA and DNA polymerase, and 5 of the 6 became negative for both marker
Therapy of chronic type B hepatitis with adenine arabinoside and adenine arabinoside monophosphate
β Scribed by Hoofnagle, Jay H.
- Book ID
- 122447378
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 555 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0168-8278
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Ten patients with chronic type B hepatitis were treated with three courses of adenine arabinoside monosphosphate (Ara-AMP). The drug was given intramuscularly at a dosage of 10 mg/kg/day in ten-day courses during each of three sequential months. The patients were all men, aged 31-61 years, who were
Adenine arabinoside monophosphate (ARA AMP) was used in ten immunosuppressed patients suffering from varicella or disseminated zoster, and compared to adenine arabinoside (vidarabine) in ten other similar patients. Good results were obtained with both drugs: the fever stopped suddenly in three or fo