𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Therapy of advanced squamous carcinoma of the lung. Cyclophosphamide versus “COMB”

✍ Scribed by Gerald P. Bodey; Stephen W. Lagakos; Alberto C. Gutierrez; Henry E. Wilson; Oleg S. Selawry

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
422 KB
Volume
39
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

✦ Synopsis

The four-drug combination of cyclophosphamide, vincristine, methyl CCNU and bleomycin was compared to CTX alone in a prospective randomized trial. Only one of 20 patients treated with COMB and one of 27 patients treated with CTX achieved a partial response. CTX was associated with a significantly better survival than COMB among patients who were ambulatory at onset of therapy. Survival among non-ambulatory patients was similar with both regimens.

Cancer 39

📜 SIMILAR VOLUMES

Advanced-staged tonsillar squamous carci
Advanced-staged tonsillar squamous carcinoma: Organ preservation versus surgical management of the primary site
✍ Haider Ali Shirazi; Ranjiv Sivanandan; Richard Goode; Willard E. Fee; Michael J. 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

## Abstract ## Background. Our aim was to review our experience in the management of advanced tonsillar squamous cell carcinoma (SCC) and to compare treatment outcomes between patients treated with and without surgery to the primary site. ## Methods. The records of 74 patients with advanced‐stag