𝔖 Bobbio Scriptorium
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Therapy for hepatic fibrosis: Revisiting the preclinical models

✍ Scribed by D. Montgomery Bissell


Book ID
119218386
Publisher
Elsevier
Year
2011
Tongue
French
Weight
191 KB
Volume
35
Category
Article
ISSN
2210-7401

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We eliminated type beta transforming growth factor (TGF-beta) signaling by adenovirus-mediated local expression of a dominant-negative type II TGF-beta receptor (AdCATbeta-TR) in the liver of rats treated with dimethylnitrosamine, a model of persistent liver fibrosis. In rats that received a single