Principles and use of anti-CTLA4 antibod
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Karl S Peggs; Sergio A Quezada; Alan J Korman; James P Allison
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Article
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2006
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Elsevier Science
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English
β 416 KB
Cytotoxic T lymphocyte antigen-4 has become recognized as one of the key negative regulators of adaptive immune responses, having a central role in the maintenance of peripheral tolerance and in shaping the repertoire of emergent T cell responses. Concurrent recognition of the potential importance o