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Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40

✍ Scribed by Sugamura, Kazuo; Ishii, Naoto; Weinberg, Andrew D.

Book ID
109954552
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
279 KB
Volume
4
Category
Article
ISSN
1474-1741

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We have previously shown that one of the co-factors required for generation of T-cell responses, 87. I, is variably expressed on melanoma cells. In the present studies we have examined the expression of another important co-factor in T-cell responses, viz., CD40, and investigated regulation of its e