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Therapeutic targeting of chemokine receptors by small molecules

โœ Scribed by Maikel Wijtmans; Danny J. Scholten; Iwan J.P. de Esch; Martine J. Smit; Rob Leurs


Book ID
118058610
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
399 KB
Volume
9
Category
Article
ISSN
1740-6749

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Small molecule antagonists for chemokine
โœ Lianne I. Willems; Ad P. IJzerman ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 648 KB

## Abstract The chemokine receptor CCR3 is believed to play a role in the development of allergic diseases such as asthma, atopic dermatitis, and allergic rhinitis. Despite the conflicting results that have been reported regarding the importance of eosinophils and CCR3 in allergic inflammation, inh