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Therapeutic strategies within the ubiquitin proteasome system

✍ Scribed by Eldridge, A G; O'Brien, T

Book ID
109842317
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
388 KB
Volume
17
Category
Article
ISSN
1350-9047

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## Abstract The ubiquitin–proteasome system (UPS) is the major proteolytic pathway that degrades intracellular proteins in a regulated manner. Deregulation of the UPS has been implicated in the pathogenesis of many neurodegenerative disorders like Alzheimer's disease, Parkinson's diseases, Huntingt