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Therapeutic serum concentrations of human alpha-1 antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes*1

โœ Scribed by KAY, M

Book ID
123552191
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
574 KB
Volume
21
Category
Article
ISSN
0270-9139

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๐Ÿ“œ SIMILAR VOLUMES

Therapeutic serum concentrations of huma
Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes
โœ Mark A. Kay; Frank Graham; Frances Leland; Savio L. C. Woo ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 559 KB

Alpha-1-antitrypsin is a relatively common genetic deficiency that results in early emphysema. The liver as the natural source of most alpha-1-antitrypsin synthesis was the target organ selected for gene replacement therapy studies. Previous work used recombinant retroviral vectors that encode the h