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Therapeutic Proteins Volume 308 || Solid-State Protein Formulation: Methodologies, Stability, and Excipient Effects

✍ Scribed by Smales, C. Mark; James, David C.


Book ID
121666765
Publisher
Humana Press
Year
2005
Weight
445 KB
Category
Article
ISBN-13
9781592599226

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Effect of sorbitol and residual moisture
✍ Liuquan (Lucy) Chang; Deanna Shepherd; Joanna Sun; Xiaolin (Charlie) Tang; Micha πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 174 KB πŸ‘ 1 views

## Purpose: To investigate the effect of plasticizers on the stability of protein formulations in the solid state and to apply these results to a study of mechanisms of protein stabilization by sugars in the solid sate. ## Methods: The igg1 antibody was formulated with either sucrose or trehalose