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Therapeutic Potential of the Proteasome Inhibitor Bortezomib on Titanium Particle-Induced Inflammation in a Murine Model

✍ Scribed by Xin Mao; Xiaoyun Pan; Tao Cheng; Xianlong Zhang


Book ID
113067009
Publisher
Springer
Year
2011
Tongue
English
Weight
333 KB
Volume
35
Category
Article
ISSN
0360-3997

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## Abstract Wear debris from total joint replacement prostheses is implicated in periprosthetic osteolysis and implant loosening. The pathophysiology of this biological process remains unclear. Animal models of particle‐induced osteolysis have proven useful in the study of specific tissue responses